Anti-Human NAPEPLD Polyclonal Antibody (HD517014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HD517014

品牌

abinScience

描述

Anti-Human NAPEPLD Polyclonal Antibody (HD517014) is a rabbit polyclonal antibody detecting NAPEPLD. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human NAPEPLD (Ser76-Phe393).

靶标

C7orf18, EC:3.1.4.54, N-acyl phosphatidylethanolamine phospholipase D, N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, NAPE-PLD, NAPE-hydrolyzing phospholipase D, NAPEPLD

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6IQ20

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (NAPEPLD) is a ~45 kDa protein. D-type phospholipase that hydrolyzes N-acyl-phosphatidylethanolamines (NAPEs) to produce bioactive N-acylethanolamines/fatty acid ethanolamides (NAEs/FAEs) and phosphatidic acid. Cleaves the terminal phosphodiester bond of diacyl- and alkenylacyl-NAPEs, primarily playing a role in the generation of long-chain saturated and monounsaturated NAEs in the brain. May control NAPE homeostasis in dopaminergic neuron membranes and regulate neuron survival, partly through RAC1 activation. As a regulator of lipid metabolism in the adipose tissue, mediates the crosstalk between adipocytes, gut microbiota and immune cells to control body temperature and weight. In particular, regulates energy homeostasis by promoting cold-induced brown or beige adipocyte differentiation program to generate heat from fatty acids and glucose.

1. Okamoto, Y. et al. (2004) The Journal of biological chemistry 279, 5298-305. PMID: 14634025

2. Wang, J. et al. (2006) The Journal of biological chemistry 281, 12325-35. PMID: 16527816

3. Magotti, P. et al. (2015) Structure (London, England : 1993) 23, 598-604. PMID: 25684574

4. Margheritis, E. et al. (2016) ACS chemical biology 11, 2908-2914. PMID: 27571266

Note

For research use only

图片

参考文献

产品说明书

Anti-Human NAPEPLD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NAPEPLD Polyclonal Antibody (HD517014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NAPEPLD Polyclonal Antibody (HD517014)

概述

图片

参考文献

产品说明书

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