Anti-Human NOTCH3 Polyclonal Antibody (HV701014)

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概述
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参考文献
产品说明书

概述

货号

HV701014

品牌

abinScience

描述

Anti-Human NOTCH3 Polyclonal Antibody (HV701014) is a rabbit polyclonal antibody detecting NOTCH3. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human NOTCH3 (Ala40-Glu467).

靶标

NOTCH3, Neurogenic locus notch homolog protein 3, Notch 3, Notch 3 extracellular truncation, Notch 3 intracellular domain

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9UM47

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Neurogenic locus notch homolog protein 3 (NOTCH3) is a ~243 kDa protein. Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD), it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

1. Peters, N. et al. (2004) Experimental cell research 299, 454-64. PMID: 15350543

2. Joutel, A. et al. (2004) American journal of human genetics 74, 338-47. PMID: 14714274

Note

For research use only

图片

参考文献

产品说明书

Anti-Human NOTCH3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NOTCH3 Polyclonal Antibody (HV701014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NOTCH3 Polyclonal Antibody (HV701014)

概述

图片

参考文献

产品说明书

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