Anti-Human EXTL3 Polyclonal Antibody (HD524014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HD524014

品牌

abinScience

描述

Anti-Human EXTL3 Polyclonal Antibody (HD524014) is a rabbit polyclonal antibody detecting EXTL3. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human EXTL3 (Tyr341-Ile540).

靶标

EC:2.4.1.223, EXT-related protein 1, EXTL1L, EXTL3, EXTR1, Exostosin-like 3, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, KIAA0519, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O43909

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Exostosin-like 3 (EXTL3) is a ~104 kDa protein. Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Initiates HS synthesis by transferring the first N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) residue (GlcNAcT-I activity) to the tetrasaccharide linker (GlcA-Gal-Gal-Xyl-)Ser core linker. May also transfer alpha-GlcNAc residues during HS elongation (GlcNAcT-II activity). Lacks glucuronyl transferase II (GlcAT-II) activity. Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs).

1. Oud, MM. et al. (2017) American journal of human genetics 100, 281-296. PMID: 28132690

2. Volpi, S. et al. (2017) The Journal of experimental medicine 214, 623-637. PMID: 28148688

3. Kim, BT. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 7176-81. PMID: 11390981

4. Wilson, LFL. et al. (2022) Nature communications 13, 3314. PMID: 35676258

5. Lai, Y. et al. (2012) Immunity 37, 74-84. PMID: 22727489

Note

For research use only

图片

参考文献

产品说明书

Anti-Human EXTL3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EXTL3 Polyclonal Antibody (HD524014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EXTL3 Polyclonal Antibody (HD524014)

概述

图片

参考文献

产品说明书

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