Anti-Human ATL2 Polyclonal Antibody (HD526014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HD526014

品牌

abinScience

描述

Anti-Human ATL2 Polyclonal Antibody (HD526014) is a rabbit polyclonal antibody detecting ATL2. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ATL2 (Val61-Gly365).

靶标

ADP-ribosylation factor-like protein 6-interacting protein 2, ARL6IP2, ATL-2, ATL2, Atlastin-2, EC:3.6.5.-

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q8NHH9

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Atlastin-2 (ATL2) is a ~66 kDa protein. Atlastin-2 (ATL2) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-2 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi).

1. Rismanchi, N. et al. (2008) Human molecular genetics 17, 1591-604. PMID: 18270207

2. Hu, J. et al. (2009) Cell 138, 549-61. PMID: 19665976

3. Morin-Leisk, J. et al. (2011) The Journal of cell biology 195, 605-15. PMID: 22065636

4. Wang, S. et al. (2016) eLife 5. PMID: 27619977

5. Crosby, D. et al. (2022) The Journal of cell biology 221. PMID: 34817557

Note

For research use only

图片

参考文献

产品说明书

Anti-Human ATL2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATL2 Polyclonal Antibody (HD526014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ATL2 Polyclonal Antibody (HD526014)

概述

图片

参考文献

产品说明书

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