Anti-Human MCM3AP Polyclonal Antibody (HD528014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HD528014

品牌

abinScience

描述

Anti-Human MCM3AP Polyclonal Antibody (HD528014) is a rabbit polyclonal antibody detecting MCM3AP. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human MCM3AP (Thr602-Gly969).

靶标

80 kDa MCM3-associated protein, EC:2.3.1.-, EC:2.3.1.48, GANP, Germinal-center associated nuclear protein, KIAA0572, MAP80, MCM3 acetylating protein, MCM3 acetyltransferase, MCM3AP

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O60318

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Germinal-center associated nuclear protein (MCM3AP) is a ~218 kDa protein. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores. Through the acetylation of histones, affects the assembly of nucleosomes at immunoglobulin variable region genes and promotes the recruitment and positioning of transcription complex to favor DNA cytosine deaminase AICDA/AID targeting, hence promoting somatic hypermutations.

1. Wickramasinghe, VO. et al. (2010) Current biology : CB 20, 25-31. PMID: 20005110

2. Okamoto, N. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 471-84. PMID: 20384790

3. Jani, D. et al. (2012) Nucleic acids research 40, 4562-73. PMID: 22307388

4. Umlauf, D. et al. (2013) Journal of cell science 126, 2656-67. PMID: 23591820

5. Singh, SK. et al. (2013) Nature communications 4, 1830. PMID: 23652018

Note

For research use only

图片

参考文献

产品说明书

Anti-Human MCM3AP Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MCM3AP Polyclonal Antibody (HD528014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human MCM3AP Polyclonal Antibody (HD528014)

概述

图片

参考文献

产品说明书

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