Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

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50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HF861014

品牌

abinScience

描述

Anti-Human ERLIN2 Polyclonal Antibody (HF861014) is a rabbit polyclonal antibody detecting ERLIN2. Suitable for Rat, Mouse, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ERLIN2 (Pro47-Asn339).

靶标

C8orf2, ERLIN2, Endoplasmic reticulum lipid raft-associated protein 2, Erlin-2, SPFH domain-containing protein 2, SPFH2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O94905

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Erlin-2 (ERLIN2) is a ~37 kDa protein. Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.

1. Pearce, MM. et al. (2007) The Journal of biological chemistry 282, 20104-15. PMID: 17502376

2. Pearce, MM. et al. (2009) The Journal of biological chemistry 284, 10433-45. PMID: 19240031

3. Jo, Y. et al. (2011) The Journal of biological chemistry 286, 15022-31. PMID: 21343306

4. Huber, MD. et al. (2013) The Journal of cell biology 203, 427-36. PMID: 24217618

Note

For research use only

图片

参考文献

产品说明书

Anti-Human ERLIN2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

概述

图片

参考文献

产品说明书

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