Anti-Human FMO5 Polyclonal Antibody (HD536014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HD536014

品牌

abinScience

描述

Anti-Human FMO5 Polyclonal Antibody (HD536014) is a rabbit polyclonal antibody detecting FMO5. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human FMO5 (Met1-Ser512).

靶标

Baeyer-Villiger monooxygenase 1, Dimethylaniline monooxygenase [N-oxide-forming] 5, Dimethylaniline oxidase 5, EC:1.14.13.-, EC:1.14.13.8, EC:1.6.3.1, FMO 5, FMO5, Flavin-containing monooxygenase 5, NADPH oxidase, hBVMO1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P49326

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Flavin-containing monooxygenase 5 (FMO5) is a ~60 kDa protein. Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (Probable). Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline.

1. Lai, WG. et al. (2011) Drug metabolism and disposition: the biological fate of chemicals 39, 61-70. PMID: 20947616

2. Fiorentini, F. et al. (2016) ACS chemical biology 11, 1039-48. PMID: 26771671

3. Fiorentini, F. et al. (2017) ACS chemical biology 12, 2379-2387. PMID: 28783300

4. Overby, LH. et al. (1995) Archives of biochemistry and biophysics 317, 275-84. PMID: 7872795

Note

For research use only

图片

参考文献

产品说明书

Anti-Human FMO5 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FMO5 Polyclonal Antibody (HD536014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FMO5 Polyclonal Antibody (HD536014)

概述

图片

参考文献

产品说明书

相关产品推荐

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