

| 货号 | HT044014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human YJEFN3 Polyclonal Antibody (HT044014) is a rabbit polyclonal antibody detecting YJEFN3. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human YJEFN3 (Met1-Leu299). | ||||||||
| 靶标 | AIBP2, ApoA-I-binding protein 2, YJEFN3, YjeF N-terminal domain-containing protein 3, YjeF_N3, hYjeF_N3 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | A6XGL0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | YjeF N-terminal domain-containing protein 3 (YJEFN3) is a ~32 kDa protein. May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis. 1. Rudolph, C. et al. (2007) Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 39, 322-35. PMID: 17533573 | ||||||||
| Note | For research use only |

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