

| 货号 | HD541014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human NCOR1 Polyclonal Antibody (HD541014) is a rabbit polyclonal antibody detecting NCOR1. Suitable for Human.
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human NCOR1 (Met424-Gly500&Trp628-Pro690). | ||||||||
| 靶标 | KIAA1047, N-CoR, N-CoR1, NCOR1, Nuclear receptor corepressor 1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O75376 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Nuclear receptor corepressor 1 (NCOR1) is a ~270 kDa protein. Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation. Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression. 1. Cui, J. et al. (2011) Cellular and molecular life sciences : CMLS 68, 1091-103. PMID: 20812024 | ||||||||
| Note | For research use only |

Lane 1: K562 cell lysate
Lane 2: NIH3T3 cell lysate
Lane 3: 293T cell lysate
Lane 4: Hela cell lysate



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