Anti-Human GPR15LG Polyclonal Antibody (HD559014)

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50ug
100ug

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概述
图片
参考文献
产品说明书

概述

货号

HD559014

品牌

abinScience

描述

Anti-Human GPR15LG Polyclonal Antibody (HD559014) is a rabbit polyclonal antibody detecting Protein GPR15LG. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human GPR15LG (Lys25-Val82).

靶标

AP-57, Antimicrobial peptide with 57 amino acid residues, Antimicrobial peptide-57, C10orf99, CSBF, Colon-derived SUSD2 binding factor, GPR15L, GPR15LG, Protein GPR15 ligand, Protein GPR15L, Protein GPR15LG, Secreted protein C10orf99

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6UWK7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Protein GPR15LG is a ~9 kDa protein. Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation.

1. Suply, T. et al. (2017) Science signaling 10. PMID: 28900043

2. Ocón, B. et al. (2017) Frontiers in immunology 8, 1111. PMID: 28936214

3. Pan, W. et al. (2014) Scientific reports 4, 6812. PMID: 25351403

4. Chen, C. et al. (2018) Scientific reports 8, 8590. PMID: 29872130

5. Tseng, PY. et al. (2022) Science advances 8, eabm7342. PMID: 35704588

Note

For research use only

图片

参考文献

产品说明书

Anti-Human GPR15LG Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GPR15LG Polyclonal Antibody (HD559014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GPR15LG Polyclonal Antibody (HD559014)

概述

图片

参考文献

产品说明书

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