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Anti-Human LACTB Polyclonal Antibody (HD571014)

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概述
货号HD571014
品牌abinScience
描述
Anti-Human LACTB Polyclonal Antibody (HD571014) is a rabbit polyclonal antibody detecting LACTB. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human LACTB (Cys100-Ser256).
靶标EC:3.4.-.-, LACTB, MRPL56, Serine beta-lactamase-like protein LACTB, mitochondrial
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P83111
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Serine beta-lactamase-like protein LACTB, mitochondrial is a ~60 kDa protein. Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism.

1. Keckesova, Z. et al. (2017) Nature 543, 681-686. PMID: 28329758
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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