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Anti-Human HTRA3 Polyclonal Antibody (HX117014)

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概述
货号HX117014
品牌abinScience
描述
Anti-Human HTRA3 Polyclonal Antibody (HX117014) is a rabbit polyclonal antibody detecting HTRA3. Suitable for Mouse, Human, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human HTRA3 (Asn141-Pro333).
靶标EC:3.4.21.-, HTRA3, High-temperature requirement factor A3, PRSP, Pregnancy-related serine protease, Serine protease HTRA3
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P83110
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Serine protease HTRA3 is a ~48 kDa protein. Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.

1. Singh, H. et al. (2011) Human reproduction (Oxford, England) 26, 748-57. PMID: 21321049
2. Singh, H. et al. (2012) BioTechniques 52, 23-8. PMID: 22229724
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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