Anti-Human KHDC3L Polyclonal Antibody (HD586014)

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概述
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参考文献
产品说明书

概述

货号

HD586014

品牌

abinScience

描述

Anti-Human KHDC3L Polyclonal Antibody (HD586014) is a rabbit polyclonal antibody detecting KHDC3L. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human KHDC3L (Met1-Ser137).

靶标

C6orf221, ECAT1, ES cell-associated transcript 1 protein, KH domain-containing protein 3, KHDC3-like protein, KHDC3L

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q587J8

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

KH domain-containing protein 3 (KHDC3L) is a ~24 kDa protein. Component of the subcortical maternal complex (SCMC), a multiprotein complex that plays a key role in early embryonic development. The SCMC complex is a structural constituent of cytoplasmic lattices, which consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos. They are required to store maternal proteins critical for embryonic development, such as proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation. KHDC3 ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function.

1. Zhang, W. et al. (2019) PLoS biology 17, e3000468. PMID: 31609975

Note

For research use only

图片

参考文献

产品说明书

Anti-Human KHDC3L Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KHDC3L Polyclonal Antibody (HD586014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KHDC3L Polyclonal Antibody (HD586014)

概述

图片

参考文献

产品说明书

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