Anti-Human ARFIP2 Polyclonal Antibody (HD593014)

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100ug

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概述
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产品说明书

概述

货号

HD593014

品牌

abinScience

描述

Anti-Human ARFIP2 Polyclonal Antibody (HD593014) is a rabbit polyclonal antibody detecting ARFIP2. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ARFIP2 (Gly81-Gln341).

靶标

ADP-ribosylation factor-interacting protein 2, ARFIP2, Arfaptin-2, POR1, Partner of RAC1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P53365

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Arfaptin-2 (ARFIP2) is a ~37 kDa protein. Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.

1. Eiseler, T. et al. (2016) The Journal of biological chemistry 291, 462-77. PMID: 26507660

2. Judith, D. et al. (2019) The Journal of cell biology 218, 1634-1652. PMID: 30917996

3. Judith, D. et al. (2019) Autophagy 15, 1660-1661. PMID: 31204568

4. Nguyen, TN. et al. (2021) Molecular cell 81, 2013-2030.e9. PMID: 33773106

5. You, DJ. et al. (2015) Cellular signalling 27, 2173-81. PMID: 26296658

Note

For research use only

图片

参考文献

产品说明书

Anti-Human ARFIP2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ARFIP2 Polyclonal Antibody (HD593014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ARFIP2 Polyclonal Antibody (HD593014)

概述

图片

参考文献

产品说明书

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