Anti-Human DKC1 Polyclonal Antibody (HD599014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HD599014

品牌

abinScience

描述

Anti-Human DKC1 Polyclonal Antibody (HD599014) is a rabbit polyclonal antibody detecting DKC1. Suitable for Mouse, Rat, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human DKC1 (Glu82-Ser295).

靶标

CBF5 homolog, DKC1, Dyskerin, EC:5.4.99.-, H/ACA ribonucleoprotein complex subunit DKC1, NOLA4, Nopp140-associated protein of 57 kDa, Nucleolar protein NAP57, Nucleolar protein family A member 4, snoRNP protein DKC1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O60832

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

H/ACA ribonucleoprotein complex subunit DKC1 is a ~57 kDa protein. Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

1. Schwartz, S. et al. (2014) Cell 159, 148-162. PMID: 25219674

2. Balogh, E. et al. (2020) Proceedings of the National Academy of Sciences of the United States of America 117, 15137-15147. PMID: 32554502

3. Venteicher, AS. et al. (2009) Science (New York, N.Y.) 323, 644-8. PMID: 19179534

Note

For research use only

图片

参考文献

产品说明书

Anti-Human DKC1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DKC1 Polyclonal Antibody (HD599014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DKC1 Polyclonal Antibody (HD599014)

概述

图片

参考文献

产品说明书

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