

| 货号 | HD601014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human LRIF1 Polyclonal Antibody (HD601014) is a rabbit polyclonal antibody detecting LRIF1. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human LRIF1 (His190-Asn311). | ||||||||
| 靶标 | C1orf103, HBiX1, HP1-binding protein enriched in inactive X chromosome protein 1, LRIF1, Ligand-dependent nuclear receptor-interacting factor 1, RIF1, Receptor-interacting factor 1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q5T3J3 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a ~84 kDa protein. Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases. Also required for silencing of the DUX4 locus in somatic cells. 1. Nozawa, RS. et al. (2013) Nature structural & molecular biology 20, 566-73. PMID: 23542155 2. Li, HJ. et al. (2007) Journal of cellular biochemistry 102, 1021-35. PMID: 17455211 3. Hamanaka, K. et al. (2020) Neurology 94, e2441-e2447. PMID: 32467133 | ||||||||
| Note | For research use only |

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