

| 货号 | HC188014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human PARD3 Polyclonal Antibody (HC188014) is a rabbit polyclonal antibody detecting PARD3. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PARD3 (Met1-Glu81&Thr583-Arg683). | ||||||||
| 靶标 | ASIP, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR-3, PAR3, PAR3-alpha, PAR3A, PARD-3, PARD3, Partitioning defective 3 homolog | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8TEW0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Partitioning defective 3 homolog (PARD3) is a ~151 kDa protein. Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. 1. Johansson, A. et al. (2000) Journal of cell science 113 ( Pt 18), 3267-75. PMID: 10954424 2. Chen, X. et al. (2017) Human mutation 38, 378-389. PMID: 27925688 3. Joberty, G. et al. (2000) Nature cell biology 2, 531-9. PMID: 10934474 4. Khazaei, MR. et al. (2009) The Journal of biological chemistry 284, 33571-9. PMID: 19812038 | ||||||||
| Note | For research use only |

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