Anti-Human TP53I3 Polyclonal Antibody (HD613014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HD613014

品牌

abinScience

描述

Anti-Human TP53I3 Polyclonal Antibody (HD613014) is a rabbit polyclonal antibody detecting TP53I3. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TP53I3 (Met1-Gln332).

靶标

EC:1.6.5.5, NADPH:quinone reductase PIG3, PIG3, Protein PIG3, Quinone oxidoreductase PIG3, TP53I3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q53FA7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Quinone oxidoreductase PIG3 (TP53I3) is a ~35 kDa protein. NADPH:quinone reductase which expression is induced by p53/TP53 and is involved in both the DNA damage response through homologous recombination repair, and p53-mediated apoptosis. Catalyzes the NADPH-dependent reduction of quinones, exhibiting a low enzymatic activity with beta-naphthoquinones and a strong preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta-naphthoquinone). Also displays a low reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol (in vitro). The reduction of 1,2-naphthoquinone concurrently generates reactive oxygen species (ROS), which may trigger apoptosis downstream of p53/TP53.

1. Porté, S. et al. (2009) The Journal of biological chemistry 284, 17194-17205. PMID: 19349281

2. Chaudhry, SR. et al. (2021) Cell death discovery 7, 62. PMID: 33782397

Note

For research use only

图片

参考文献

产品说明书

Anti-Human TP53I3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TP53I3 Polyclonal Antibody (HD613014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TP53I3 Polyclonal Antibody (HD613014)

概述

图片

参考文献

产品说明书

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