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Anti-Human UGDH Polyclonal Antibody (HA400014)

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规格:
  • 50ug
  • 100ug
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概述
货号HA400014
品牌abinScience
描述
Anti-Human UGDH Polyclonal Antibody (HA400014) is a rabbit polyclonal antibody detecting UGDH. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human UGDH (Met1-Val494).
靶标EC:1.1.1.22, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGDH
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号O60701
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

UDP-glucose 6-dehydrogenase (UGDH) is a ~55 kDa protein. Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans. Required for proper brain and neuronal development.

1. Egger, S. et al. (2011) The Journal of biological chemistry 286, 23877-87. PMID: 21502315
2. Sennett, NC. et al. (2011) Biochemistry 50, 9651-63. PMID: 21961565
3. Egger, S. et al. (2012) The Journal of biological chemistry 287, 2119-29. PMID: 22123821
4. Sennett, NC. et al. (2012) Biochemistry 51, 9364-74. PMID: 23106432
5. Kadirvelraj, R. et al. (2014) Biochemistry 53, 8043-51. PMID: 25478983
6. Beattie, NR. et al. (2017) Biochemistry 56, 202-211. PMID: 27966912
7. Keul, ND. et al. (2018) Nature 563, 584-588. PMID: 30420606
8. Beattie, NR. et al. (2018) Biochemistry 57, 6848-6859. PMID: 30457329
9. Hengel, H. et al. (2020) Nature communications 11, 595. PMID: 32001716
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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