

| 货号 | HW681014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human AGTR2 Polyclonal Antibody (HW681014) is a rabbit polyclonal antibody detecting AGTR2. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AGTR2 (Lys2-Asp45&Arg182-Gln206&Val321-Ser363). | ||||||||
| 靶标 | AGTR2, AT2 receptor, Angiotensin II type-2 receptor, Type-2 angiotensin II receptor | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P50052 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Type-2 angiotensin II receptor (AGTR2) is a ~41 kDa protein. Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. 1. Zhang, H. et al. (2017) Nature 544, 327-332. PMID: 28379944 2. Asada, H. et al. (2018) Nature structural & molecular biology 25, 570-576. PMID: 29967536 3. Asada, H. et al. (2020) Structure (London, England : 1993) 28, 418-425.e4. PMID: 31899086 4. Tsuzuki, S. et al. (1994) Biochemical and biophysical research communications 200, 1449-54. PMID: 8185599 5. Nouet, S. et al. (2004) The Journal of biological chemistry 279, 28989-97. PMID: 15123706 | ||||||||
| Note | For research use only |

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