Anti-Human ADRB1 Polyclonal Antibody (HY486014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HY486014

品牌

abinScience

描述

Anti-Human ADRB1 Polyclonal Antibody (HY486014) is a rabbit polyclonal antibody detecting ADRB1. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ADRB1 (Gly2-Gln55&His197-Arg222).

靶标

ADRB1, ADRB1R, B1AR, Beta-1 adrenergic receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P08588

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes.

1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248

2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161

3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775

4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660

5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857

6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867

7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062

Note

For research use only

图片

参考文献

产品说明书

Anti-Human ADRB1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ADRB1 Polyclonal Antibody (HY486014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ADRB1 Polyclonal Antibody (HY486014)

概述

图片

参考文献

产品说明书

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