Anti-Human GPR37L1 Polyclonal Antibody (HD416014)

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概述
图片
参考文献
产品说明书

概述

货号

HD416014

品牌

abinScience

描述

Anti-Human GPR37L1 Polyclonal Antibody (HD416014) is a rabbit polyclonal antibody detecting GPR37L1. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human GPR37L1 (Ala26-Met134).

靶标

ETBR-LP-2, ETBRLP2, Endothelin B receptor-like protein 2, G-protein coupled receptor 37-like 1, GPR37L1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O60883

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

G-protein coupled receptor 37-like 1 (GPR37L1) is a ~52 kDa protein. G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway.

1. Coleman, JL. et al. (2016) Science signaling 9, ra36. PMID: 27072655

2. Meyer, RC. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 9529-34. PMID: 23690594

3. Giddens, MM. et al. (2017) Neurobiology of disease 106, 181-190. PMID: 28688853

Note

For research use only

图片

参考文献

产品说明书

Anti-Human GPR37L1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GPR37L1 Polyclonal Antibody (HD416014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GPR37L1 Polyclonal Antibody (HD416014)

概述

图片

参考文献

产品说明书

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