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Anti-Human ING5 Polyclonal Antibody (HD420014)

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  • 100ug
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概述
货号HD420014
品牌abinScience
描述
Anti-Human ING5 Polyclonal Antibody (HD420014) is a rabbit polyclonal antibody detecting ING5. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ING5 (Ala2-Ala105).
靶标ING5, Inhibitor of growth protein 5, p28ING5
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q8WYH8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Inhibitor of growth protein 5 (ING5) is a ~27 kDa protein. Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner.

1. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767
2. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653
3. Shiseki, M. et al. (2003) Cancer research 63, 2373-8. PMID: 12750254
4. Zhang, F. et al. (2011) PloS one 6, e21505. PMID: 21750715
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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