

| 货号 | HD420014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human ING5 Polyclonal Antibody (HD420014) is a rabbit polyclonal antibody detecting ING5. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ING5 (Ala2-Ala105). | ||||||||
| 靶标 | ING5, Inhibitor of growth protein 5, p28ING5 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8WYH8 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Inhibitor of growth protein 5 (ING5) is a ~27 kDa protein. Component of the HBO1 complex, which specifically mediates acetylation of histone H3 at 'Lys-14' (H3K14ac) and, to a lower extent, acetylation of histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator. Inhibits cell growth, induces a delay in S-phase progression and enhances Fas-induced apoptosis in an INCA1-dependent manner. 1. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767 2. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653 3. Shiseki, M. et al. (2003) Cancer research 63, 2373-8. PMID: 12750254 4. Zhang, F. et al. (2011) PloS one 6, e21505. PMID: 21750715 | ||||||||
| Note | For research use only |

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