

| 货号 | HX086014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human EPHB4 Polyclonal Antibody (HX086014) is a rabbit polyclonal antibody detecting EPHB4. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human EPHB4 (Leu16-Ala539). | ||||||||
| 靶标 | EC:2.7.10.1, EPHB4, Ephrin type-B receptor 4, HTK, Hepatoma transmembrane kinase, MYK1, TYRO11, Tyrosine-protein kinase TYRO11 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P54760 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Ephrin type-B receptor 4 (EPHB4) is a ~108 kDa protein. Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. | ||||||||
| Note | For research use only |

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