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Anti-HSV-2/HHV-2 glycoprotein H/gH Polyclonal Antibody (VK081024)

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规格:
  • 50ug
  • 100ug
数量:
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概述
货号VK081024
品牌abinScience
描述
Anti-HSV-2/HHV-2 glycoprotein H/gH Polyclonal Antibody (VK081024) is a rabbit polyclonal antibody detecting HSV-2/HHV-2 glycoprotein H/gH. Suitable for Human herpesvirus 2.
种属反应性Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2)
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant HSV-2/HHV-2 glycoprotein H/gH (Arg49-Pro803).
靶标Envelope glycoprotein H, gH
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P89445
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Envelope glycoprotein H (gH) is a ~89 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Interaction with host integrins ITGAV/ITGB3 triggers release of cytosolic Ca(2+) and FAK phosphorylation leading to efficient viral entry into host genital tract epithelial cells.

1. Cheshenko, N. et al. (2014) Journal of virology 88, 10026-38. PMID: 24942591
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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