Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

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概述
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概述

货号

MD634014

品牌

abinScience

描述

Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014) is a rabbit polyclonal antibody detecting Serpinb1a. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse Serpinb1a (Met1-Pro379).

靶标

Leukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9D154

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Leukocyte elastase inhibitor A (Serpinb1a) is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H.

1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292

2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149

3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252

4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621

5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154

6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse Serpinb1a Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

概述

图片

参考文献

产品说明书

相关产品推荐

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