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Anti-Mouse FGA Polyclonal Antibody (MF809014)

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概述
货号MF809014
品牌abinScience
描述
Anti-Mouse FGA Polyclonal Antibody (MF809014) is a rabbit polyclonal antibody detecting Fga. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse FGA (Thr552-Gln789).
靶标Fga, Fibrinogen alpha chain, Fibrinopeptide A
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号E9PV24
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Fibrinogen alpha chain (FGA) is a ~87 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.

1. Suh, TT. et al. (1995) Genes & development 9, 2020-33. PMID: 7649481
2. Drew, AF. et al. (2001) Blood 97, 3691-8. PMID: 11389004
3. Ni, H. et al. (2000) The Journal of clinical investigation 106, 385-92. PMID: 10930441
4. Yang, H. et al. (2009) Blood 114, 425-36. PMID: 19332769
5. Johnson, LL. et al. (2003) The Journal of experimental medicine 197, 801-6. PMID: 12629066
6. Luo, D. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 4149-61. PMID: 23487423
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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