Anti-Mouse CCDC88B Polyclonal Antibody (MD635014)

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概述
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参考文献
产品说明书

概述

货号

MD635014

品牌

abinScience

描述

Anti-Mouse CCDC88B Polyclonal Antibody (MD635014) is a rabbit polyclonal antibody detecting Ccdc88b. Suitable for Mouse.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse CCDC88B (Met1-Leu236).

靶标

Ccdc88, Ccdc88b, Coiled-coil domain-containing protein 88B, Gipie, HkRP3, Hook-related protein 3

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q4QRL3

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Coiled-coil domain-containing protein 88B (CCDC88B) is a ~166 kDa protein. Acts as a positive regulator of T-cell maturation and inflammatory function. Required for several functions of T-cells in both the CD4(+) and the CD8(+) compartments and this includes expression of cell surface markers of activation, proliferation, and cytokine production in response to specific or non-specific stimulation and during the course of infection with the mouse malaria parasite Plasmodium berghei. Enhances NK cell cytotoxicity by positively regulating polarization of microtubule-organizing center (MTOC) to cytotoxic synapse, lytic granule transport along microtubules, and dynein-mediated clustering to MTOC. Interacts with HSPA5 and stabilizes the interaction between HSPA5 and ERN1, leading to suppression of ERN1-induced JNK activation and endoplasmic reticulum stress-induced apoptosis.

1. Kennedy, JM. et al. (2014) The Journal of experimental medicine 211, 2519-35. PMID: 25403443

2. Matsushita, E. et al. (2011) Molecular biology of the cell 22, 736-47. PMID: 21289099

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse CCDC88B Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CCDC88B Polyclonal Antibody (MD635014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CCDC88B Polyclonal Antibody (MD635014)

概述

图片

参考文献

产品说明书

相关产品推荐

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