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Anti-Reovirus Outer capsid protein sigma-1 Polyclonal Antibody (VK138014)

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概述
货号VK138014
品牌abinScience
描述
Anti-Reovirus Outer capsid protein sigma-1 Polyclonal Antibody (VK138014) is a rabbit polyclonal antibody detecting Outer capsid protein sigma-1. Suitable for Reovirus type 1.
种属反应性Mammalian orthoreovirus 1 (MRV1)
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Reovirus Outer capsid protein sigma-1 (Val258-Arg470).
靶标Cell attachment protein, Hemagglutinin, Outer capsid protein sigma-1, S1, Sigma1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P04506
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Outer capsid protein sigma-1 is a ~51 kDa protein. Fiber-like molecule that attaches the virion to the host cell membrane by binding with initial low affinity to sialic acid containing proteins, followed by high-affinity bindingto the entry receptor F11R/JAM-A. Also binds to the ganglioside GM2 as an alternate receptor, this binding is serotype-specific. The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis.

1. Reiss, K. et al. (2012) PLoS pathogens 8, e1003078. PMID: 23236285
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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