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Anti-Mouse NUMB Polyclonal Antibody (MW709014)

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概述
货号MW709014
品牌abinScience
描述
Anti-Mouse NUMB Polyclonal Antibody (MW709014) is a rabbit polyclonal antibody detecting h-Numb. Suitable for Rat, Mouse, and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse NUMB (Val16-Ala200).
靶标C14orf41, NUMB, Protein S171, Protein numb homolog, h-Numb
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q9QZS3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Protein numb homolog is a ~70 kDa protein. Regulates clathrin-mediated receptor endocytosis. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity.

1. Zhong, W. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 6844-9. PMID: 10841580
2. Petersen, PH. et al. (2002) Nature 419, 929-34. PMID: 12410312
3. Petersen, PH. et al. (2004) Nature neuroscience 7, 803-11. PMID: 15273690
4. Kuo, CT. et al. (2006) Cell 127, 1253-64. PMID: 17174898
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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