Anti-Human Glucagon R/GCGR Polyclonal Antibody (HW547014)

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概述
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参考文献
产品说明书

概述

货号

HW547014

品牌

abinScience

描述

Anti-Human GCGR Polyclonal Antibody (HW547014) is a rabbit polyclonal antibody detecting GCGR. Suitable for Mouse, Rat, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human GCGR (Ala26-Lys136).

靶标

GCGR, GL-R, Glucagon receptor

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P47871

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Glucagon receptor (GCGR) is a ~54 kDa protein. G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase.

1. Qiao, A. et al. (2020) Science (New York, N.Y.) 367, 1346-1352. PMID: 32193322

2. Cong, Z. et al. (2024) Cell discovery 10, 18. PMID: 38346960

Note

For research use only

图片

参考文献

产品说明书

Anti-Human Glucagon R/GCGR Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Glucagon R/GCGR Polyclonal Antibody (HW547014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Glucagon R/GCGR Polyclonal Antibody (HW547014)

概述

图片

参考文献

产品说明书

相关产品推荐

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