

| 货号 | HV730014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human PLCD3 Polyclonal Antibody (HV730014) is a rabbit polyclonal antibody detecting PLCD3. Suitable for Mouse and Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PLCD3 (Pro46-Leu251). | ||||||||
| 靶标 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, EC:3.1.4.11, KIAA1964, PLC-delta-3, PLCD3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8N3E9 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (PLCD3) is a ~89 kDa protein. Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling. 1. Pawelczyk, T. et al. (1999) European journal of biochemistry 262, 291-8. PMID: 10336610 | ||||||||
| Note | For research use only |

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