

| 货号 | MV664014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse GP6 Polyclonal Antibody (MV664014) is a rabbit polyclonal antibody detecting GP6. Suitable for Mouse.
| ||||||||
| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse GP6 (Ser101-Leu206). | ||||||||
| 靶标 | GP6, GPVI, Glycoprotein 6, Platelet glycoprotein VI | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P0C191 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 背景 | Platelet glycoprotein VI (GP6) is a ~34 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. 1. Lockyer, S. et al. (2006) Thrombosis research 118, 371-80. PMID: 16139873 2. Pokidysheva, E. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 161-6. PMID: 24368846 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-GP6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: SH-SY5Y cell lysate



24小时产品查询

扫一扫关注我们

专属渠道经理