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Anti-Mouse IL19 Polyclonal Antibody (MV492014)

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概述
货号MV492014
品牌abinScience
描述
Anti-Mouse IL19 Polyclonal Antibody (MV492014) is a rabbit polyclonal antibody detecting IL19. Suitable for Mouse.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Mouse IL19 (Leu25-Ala176).
靶标IL-19, IL19, Interleukin-19, Melanoma differentiation-associated protein-like protein, NG.1, ZMDA1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q8CJ70
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Interleukin-19 (IL19) is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL5. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3.

1. Liao, YC. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 169, 4288-97. PMID: 12370360
2. Kako, F. et al. (2016) American journal of physiology. Cell physiology 310, C931-41. PMID: 27053520
3. Liao, SC. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6712-8. PMID: 15557163
4. Xiao, M. et al. (2021) Blood 137, 3533-3547. PMID: 33684929
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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