Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody (MV234014)

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概述
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参考文献
产品说明书

概述

货号

MV234014

品牌

abinScience

描述

Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody (MV234014) is a rabbit polyclonal antibody detecting SIGLEC1. Suitable for Mouse.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Mouse CD169/SIGLEC1 (Gly22-Val235).

靶标

CD169, SIGLEC1, SN, Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q62230

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Sialoadhesin (CD169/SIGLEC1) is a ~182 kDa protein. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response. Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs). In turn, enhances macrophage-to-T-cell transmission of several viruses including murine leukemia virus. Acts as an endocytic receptor mediating clathrin dependent endocytosis.

1. Chang, YC. et al. (2014) Journal of molecular medicine (Berlin, Germany) 92, 951-9. PMID: 24788876

2. Erikson, E. et al. (2015) The Journal of biological chemistry 290, 27345-27359. PMID: 26370074

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody (MV234014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody (MV234014)

概述

图片

参考文献

产品说明书

相关产品推荐

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