Anti-Human DBR1 Polyclonal Antibody (HV163014)

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概述
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参考文献
产品说明书

概述

货号

HV163014

品牌

abinScience

描述

Anti-Human DBR1 Polyclonal Antibody (HV163014) is a rabbit polyclonal antibody detecting DBR1. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human DBR1 (Met1-Pro273).

靶标

DBR1, EC:3.1.4.-, Lariat debranching enzyme

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9UK59

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Lariat debranching enzyme (DBR1) is a ~61 kDa protein. Cleaves the 2'-5' phosphodiester linkage at the branch point of excised lariat intron RNA and converts them into linear molecules that can be subsequently degraded, thereby facilitating ribonucleotide turnover. Linked to its role in pre-mRNA processing mechanism, may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis and have an antiviral cell-intrinsic defense function in the brainstem.

1. Kim, JW. et al. (2000) Nucleic acids research 28, 3666-73. PMID: 10982890

2. Ye, Y. et al. (2005) Retrovirology 2, 63. PMID: 16232320

3. Arenas, J. et al. (1987) The Journal of biological chemistry 262, 4274-9. PMID: 2435736

4. Zhang, SY. et al. (2018) Cell 172, 952-965.e18. PMID: 29474921

Note

For research use only

图片

参考文献

产品说明书

Anti-Human DBR1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DBR1 Polyclonal Antibody (HV163014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DBR1 Polyclonal Antibody (HV163014)

概述

图片

参考文献

产品说明书

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