

| 货号 | MT448014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse LGALS8 Polyclonal Antibody (MT448014) is a rabbit polyclonal antibody detecting LGALS8. Suitable for Mouse.
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse LGALS8 (Met1-Ala163). | ||||||||
| 靶标 | Gal-8, Galectin-8, LGALS8, PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9JL15 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Galectin-8 (LGALS8) is a ~36 kDa protein. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. | ||||||||
| Note | For research use only |

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