Anti-Human DEFB4A Polyclonal Antibody (HT380014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HT380014

品牌

abinScience

描述

Anti-Human DEFB4A Polyclonal Antibody (HT380014) is a rabbit polyclonal antibody detecting DEFB4A. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human DEFB4A (Gly24-Pro64).

靶标

BD-2, Beta-defensin 2, DEFB102, DEFB2, DEFB4, DEFB4A, Defensin beta 4A, Defensin, beta 2, SAP1, Skin-antimicrobial peptide 1, hBD-2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O15263

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Defensin beta 4A (DEFB4A) is a ~7 kDa protein. Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria. Antimicrobial activity against P.aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM. Also exhibits antimicrobial activity against the yeast C.albicans. Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death. Acts as a ligand for C-C chemokine receptor CCR6.

1. Harder, J. et al. (2000) American journal of respiratory cell and molecular biology 22, 714-21. PMID: 10837369

2. Harder, J. et al. (1997) Nature 387, 861. PMID: 9202117

3. Järvå, M. et al. (2018) Science advances 4, eaat0979. PMID: 30050988

4. Yang, D. et al. (1999) Science (New York, N.Y.) 286, 525-8. PMID: 10521347

5. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036

Note

For research use only

图片

参考文献

产品说明书

Anti-Human DEFB4A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DEFB4A Polyclonal Antibody (HT380014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DEFB4A Polyclonal Antibody (HT380014)

概述

图片

参考文献

产品说明书

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