Anti-Human DHH Polyclonal Antibody (HT127014)

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概述
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产品说明书

概述

货号

HT127014

品牌

abinScience

描述

Anti-Human DHH Polyclonal Antibody (HT127014) is a rabbit polyclonal antibody detecting DHH-N. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human DHH (Gly202-Gly396).

靶标

DHH, DHH-N, Desert hedgehog protein, Desert hedgehog protein N-product, EC:3.1.-.-, HHG-3

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O43323

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Desert hedgehog protein (DHH) is a ~43 kDa protein. The C-terminal part of the desert hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (N-product and C-product) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product (DHH-N). Both activities occur in the endoplasmic reticulum. Once cleaved, the C-product is degraded in the endoplasmic reticulum. Functions in cell-cell mediated juxtacrine signaling.

1. Pettigrew, CA. et al. (2014) Mechanisms of development 131, 137-49. PMID: 24342078

2. Hollier, PL. et al. (2021) Cardiovascular research 117, 2489-2501. PMID: 33063110

Note

For research use only

图片

参考文献

产品说明书

Anti-Human DHH Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DHH Polyclonal Antibody (HT127014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DHH Polyclonal Antibody (HT127014)

概述

图片

参考文献

产品说明书

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