Anti-Mouse TRADD Polyclonal Antibody (MS785014)

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概述
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产品说明书

概述

货号

MS785014

品牌

abinScience

描述

Anti-Mouse TRADD Polyclonal Antibody (MS785014) is a rabbit polyclonal antibody detecting TRADD. Suitable for Mouse.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse TRADD (Trp11-Gln142).

靶标

TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD, Tumor necrosis factor receptor type 1-associated DEATH domain protein

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q3U0V2

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) is a ~34 kDa protein. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.

1. Chio, II. et al. (2012) Nature cell biology 14, 625-33. PMID: 22561347

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse TRADD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse TRADD Polyclonal Antibody (MS785014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse TRADD Polyclonal Antibody (MS785014)

概述

图片

参考文献

产品说明书

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