

| 货号 | HS728014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human MEP1B Polyclonal Antibody (HS728014) is a rabbit polyclonal antibody detecting MEP1B. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MEP1B (Ile37-Tyr253). | ||||||||
| 靶标 | EC:3.4.24.63, Endopeptidase-2, MEP1B, Meprin A subunit beta, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q16820 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Meprin A subunit beta (MEP1B) is a ~79 kDa protein. Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components. 1. Schmidt, F. et al. (2016) Biological chemistry. PMID: 27180357 | ||||||||
| Note | For research use only |

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