Anti-Human KDM2A Polyclonal Antibody (HP303014)

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50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HP303014

品牌

abinScience

描述

Anti-Human KDM2A Polyclonal Antibody (HP303014) is a rabbit polyclonal antibody detecting KDM2A. Suitable for Human and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human KDM2A (Thr931-Ser1162).

靶标

CXXC-type zinc finger protein 8, CXXC8, EC:1.14.11.27, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, FBL11, FBL7, FBXL11, JHDM1A, JmjC domain-containing histone demethylation protein 1A, KDM2A, KIAA1004, Lysine-specific demethylase 2A, [Histone-H3]-lysine-36 demethylase 1A

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9Y2K7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Lysine-specific demethylase 2A (KDM2A) is a ~132 kDa protein. Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere.

1. Reischl, S. et al. (2015) Journal of biological rhythms 30, 291-301. PMID: 26037310

Note

For research use only

图片

参考文献

产品说明书

Anti-Human KDM2A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM2A Polyclonal Antibody (HP303014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM2A Polyclonal Antibody (HP303014)

概述

图片

参考文献

产品说明书

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