

| 货号 | HF543014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human IL33 Polyclonal Antibody (HF543014) is a rabbit polyclonal antibody detecting IL33. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human IL33 (Ser112-Thr270). | ||||||||
| 靶标 | C9orf26, IL-1F11, IL-33, IL1F11, IL33, Interleukin-1 family member 11, Interleukin-33, Interleukin-33 (109-270), Interleukin-33 (95-270), Interleukin-33 (99-270), NF-HEV, NFHEV, Nuclear factor from high endothelial venules | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O95760 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Interleukin-33 (IL33) is a ~30 kDa protein. Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as an enhancer of polarization of alternatively activated macrophages. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury. 1. Schmitz, J. et al. (2005) Immunity 23, 479-90. PMID: 16286016 2. Kurowska-Stolarska, M. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 6469-77. PMID: 19841166 3. Komai-Koma, M. et al. (2007) European journal of immunology 37, 2779-86. PMID: 17853410 4. Moussion, C. et al. (2008) PloS one 3, e3331. PMID: 18836528 | ||||||||
| Note | For research use only |

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