Anti-Human TSPAN4 Polyclonal Antibody (HD423014)

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50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HD423014

品牌

abinScience

描述

Anti-Human TSPAN4 Polyclonal Antibody (HD423014) is a rabbit polyclonal antibody detecting TSPAN4. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TSPAN4 (Tyr107-Asn201).

靶标

NAG-2, NAG2, Novel antigen 2, TM4SF7, TSPAN4, Tetraspanin-4, Transmembrane 4 superfamily member 7, Tspan-4

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O14817

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Tetraspanin-4 (TSPAN4) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays an essential role in migrasome formation and migration on retracting fibers at the rear end of migrating cells. Migrasomes are cellular organelles that form as large vesicle-like structures on retraction fibers of migrating cells. Mechanistically, acts as a membrane curvature sensor and participates in stabilizing the migrasome structure in a late stage of biogenesis. May also play a regulatory role for the histamine H4 receptor/HRH4 without affecting histamine binding to HRH4 or signaling.

1. Huang, Y. et al. (2019) Nature cell biology 21, 991-1002. PMID: 31371828

2. Dharan, R. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2208993119. PMID: 36252000

3. Dharan, R. et al. (2023) Nature communications 14, 1037. PMID: 36823145

4. Ma, X. et al. (2021) Biomolecules 11. PMID: 34439793

Note

For research use only

图片

参考文献

产品说明书

Anti-Human TSPAN4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSPAN4 Polyclonal Antibody (HD423014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSPAN4 Polyclonal Antibody (HD423014)

概述

图片

参考文献

产品说明书

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