Anti-Human WDR81 Polyclonal Antibody (HD280014)

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概述
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参考文献
产品说明书

概述

货号

HD280014

品牌

abinScience

描述

Anti-Human WDR81 Polyclonal Antibody (HD280014) is a rabbit polyclonal antibody detecting WDR81. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human WDR81 (Gly337-Gln614).

靶标

WD repeat-containing protein 81, WDR81

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q562E7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

WD repeat-containing protein 81 (WDR81) is a ~211 kDa protein. Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated protein aggregates. In this process, may regulate the interaction of SQSTM1 with ubiquitinated proteins and also recruit MAP1LC3C.

1. Liu, K. et al. (2016) The Journal of cell biology 212, 181-98. PMID: 26783301

2. Rapiteanu, R. et al. (2016) Traffic (Copenhagen, Denmark) 17, 940-58. PMID: 27126989

3. Liu, X. et al. (2017) The Journal of cell biology 216, 1301-1320. PMID: 28404643

Note

For research use only

图片

参考文献

产品说明书

Anti-Human WDR81 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human WDR81 Polyclonal Antibody (HD280014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human WDR81 Polyclonal Antibody (HD280014)

概述

图片

参考文献

产品说明书

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