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Anti-Human NCAPD2 Polyclonal Antibody (HD230014)

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概述
货号HD230014
品牌abinScience
描述
Anti-Human NCAPD2 Polyclonal Antibody (HD230014) is a rabbit polyclonal antibody detecting NCAPD2. Suitable for Human.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human NCAPD2 (Met1-Thr400).
靶标CAPD2, CNAP1, Chromosome condensation-related SMC-associated protein 1, Chromosome-associated protein D2, Condensin complex subunit 1, KIAA0159, NCAPD2, Non-SMC condensin I complex subunit D2, XCAP-D2 homolog, hCAP-D2
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q15021
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Condensin complex subunit 1 (NCAPD2) is a ~157 kDa protein. Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. May target the condensin complex to DNA via its C-terminal domain. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation.

1. Kimura, K. et al. (2001) The Journal of biological chemistry 276, 5417-20. PMID: 11136719
2. Martin, CA. et al. (2016) Genes & development 30, 2158-2172. PMID: 27737959
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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