Anti-Human PTGR1 Polyclonal Antibody (HD224014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HD224014

品牌

abinScience

描述

Anti-Human PTGR1 Polyclonal Antibody (HD224014) is a rabbit polyclonal antibody detecting PTGR1. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human PTGR1 (Met1-Ala329).

靶标

15-oxoprostaglandin 13-reductase, D3T-inducible gene 1 protein, DIG-1, Dithiolethione-inducible gene 1 protein, EC:1.3.1.48, EC:1.3.1.74, LTB4DH, Leukotriene B4 12-hydroxydehydrogenase, NAD(P)H-dependent alkenal/one oxidoreductase, PRG-1, PTGR1, Prostaglandin reductase 1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q14914

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Prostaglandin reductase 1 (PTGR1) is a ~35 kDa protein. NAD(P)H-dependent oxidoreductase involved in metabolic inactivation of pro- and anti-inflammatory eicosanoids: prostaglandins (PG), leukotrienes (LT) and lipoxins (LX). Catalyzes with high efficiency the reduction of the 13,14 double bond of 15-oxoPGs, including 15-oxo-PGE1, 15-oxo-PGE2, 15-oxo-PGF1-alpha and 15-oxo-PGF2-alpha. Catalyzes with lower efficiency the oxidation of the hydroxyl group at C12 of LTB4 and its derivatives, converting them into biologically less active 12-oxo-LTB4 metabolites. Reduces 15-oxo-LXA4 to 13,14 dihydro-15-oxo-LXA4, enhancing neutrophil recruitment at the inflammatory site. May play a role in metabolic detoxification of alkenals and ketones.

1. Mesa, J. et al. (2015) Chemico-biological interactions 234, 105-13. PMID: 25619643

Note

For research use only

图片

参考文献

产品说明书

Anti-Human PTGR1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PTGR1 Polyclonal Antibody (HD224014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PTGR1 Polyclonal Antibody (HD224014)

概述

图片

参考文献

产品说明书

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