

| 货号 | HD173014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human INCA1 Polyclonal Antibody (HD173014) is a rabbit polyclonal antibody detecting Protein INCA1. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human INCA1 (Gln2-Glu236). | ||||||||
| 靶标 | INCA1, Inhibitor of CDK interacting with cyclin A1, Protein INCA1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q0VD86 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Protein INCA1 is a ~26 kDa protein. Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and cell proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. 1. Bäumer, N. et al. (2011) The Journal of biological chemistry 286, 28210-22. PMID: 21540187 | ||||||||
| Note | For research use only |

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