

| 货号 | HD132014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human MBLAC1 Polyclonal Antibody (HD132014) is a rabbit polyclonal antibody detecting MBLAC1. Suitable for Human.
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MBLAC1 (Arg2-Arg236). | ||||||||
| 靶标 | EC:3.1.27.-, Endoribonuclease MBLAC1, MBLAC1, Metallo-beta-lactamase domain-containing protein 1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | A4D2B0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Metallo-beta-lactamase domain-containing protein 1 (MBLAC1) is a ~27 kDa protein. Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage. 1. Pettinati, I. et al. (2018) eLife 7. PMID: 30507380 | ||||||||
| Note | For research use only |

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