

| 货号 | HD110014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human UBE2G2 Polyclonal Antibody (HD110014) is a rabbit polyclonal antibody detecting UBE2G2. Suitable for Mouse and Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human UBE2G2 (Met1-Leu165). | ||||||||
| 靶标 | E2 ubiquitin-conjugating enzyme G2, EC:2.3.2.23, UBC7, UBE2G2, Ubiquitin carrier protein G2, Ubiquitin-conjugating enzyme E2 G2, Ubiquitin-protein ligase G2 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P60604 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) is a ~18 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation. 1. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386 2. Sato, T. et al. (2012) Molecular cell 47, 99-110. PMID: 22607976 3. Jo, Y. et al. (2013) Molecular biology of the cell 24, 169-83. PMID: 23223569 | ||||||||
| Note | For research use only |

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